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Roots extract of plant can be used for snake Bite

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T. Nandakumar: Scientists from the University of Kerala and the Kerala State Biodiversity Board (KSBB) have come up with evidence that the root extract of a plant endemic to the Western Ghats and the evergreen forests in the Indian subcontinent is effective against the venom of the Russell’s viper.

The study, published in the latest edition of the Journal of Ethnopharmacology brought out by Elsevier, provides scientific validation of folk medicine practised by tribal healers. The extract of Ophiorrhiza mungos, commonly known as Keeri pacha or Keeri purandan in Malayalam, was found to neutralise the venom of the Russell’s viper ( Daboia russelii ). A potent haemotoxin, the viper venom acts on the circulatory system, bringing about coagulation of the blood and clotting of the pulmonary arteries in bite victims. It can cause death unless a remedy is speedily applied.

Insensate model tested

The study found that the root extract of O. mungos had compounds with the power to neutralise the viper venom and inhibit its activity. The research team, including Anaswara Krishnan S. from the Department of Zoology, Dileepkumar R. from the Centre for Venom Informatics, Achuthsankar S. Nair from the Department of Computational Biology and Bioinformatics under the university, and Oommen V. Oommen, Chairman, KSBB, used early-developing chick embryos as an insensate model to test the efficacy of the anti-venom. The plant root extract was found to abolish traces of haemorrhagic lesions induced by the viper venom in the chick embryos.

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